CLADETM 5 LONGEVITY PATHWAYS · 1 DAILY PROTOCOL · FREE SHIPPING

Breakfast-table routine with CLADE Longevity Complex

CLADE™ Longevity Complex NAD+ and Polyphenol Cellular Protocol supplement bottle

★★★★★ 4.8 from 741 Reviews | 6 Actives | 90-Day Guarantee

Longevity Support That
Replaces the Multi-Bottle Stack

NMN and Trigonelline restore NAD+ signaling. Testosurge apigenin protects it from CD38. Resveratrol and grape-derived OPCs cover the antioxidant side. Give all six actives 90 days to compound and your cells have the conditions to function closer to how they did a decade ago.

Polyphenol Defense

Resveratrol 95 at 300mg, dosed on the label

OPC Reinforcement

Vinomerix Optima® 210mg: grape-derived OPCs

NAD+ Boost

Two routes: NMN 255mg + Trigonelline 60mg (Nature)

NAD+ Shield

Testosurge® 150mg blocks CD38 that destroys 90% of NAD+

Value

5 synergistic pathways for $79/mo vs buying each separately. $2.17/day (quarterly)

GMP Certified

Third-Party Tested

Non-GMO

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SAVE 34% + FREE SHIPPING BEST RESULTS

Six actives. Ninety days. Give your cells the full compounding arc.

Billed $195.00 USD every 12 weeks

$2.17 / DAY

📅 Day 30: NAD+ pathway support engages; daily energy steadies and mid-afternoon dips ease.

📅 Day 60: Mitochondrial renewal deepens; recovery between workouts shortens and mental clarity holds later in the day.

📅 Day 90: All six actives have had time to compound; the protocol becomes the biological baseline your body expects.

🎁 FREE Welcome Guide: Your Longevity Protocol (Worth $26)

🔒 No commitment. Pause or cancel anytime in your account.

Billed $79.00 USD every 4 weeks

$2.63 / DAY

One-time. No subscription.

$3.30 / DAY

No commitment. Pause or cancel anytime. One click in your account.

Ships to United States in 3-5 days FREE

90-Day Cellular Progress Guarantee

If your daily energy, recovery, or biological-age trajectory haven't shifted after giving every pathway 90 days to compound, contact us for a full refund. No forms, no restocking fee.

Resveratrol 95 300 mg The most studied polyphenol in longevity research, at a printed dose

Vinomerix Optima® 210 mg Grape-derived OPCs. A second, distinct antioxidant source.

NMN (Nicotinamide Mononucleotide) 255 mg Part of the dual-route NAD+ system with Testosurge CD38 protection

Testosurge® (Apigenin-rich) 150 mg Blocks CD38 enzyme that destroys 90% of NAD+ with age

Trigonelline 50% 60 mg Preiss-Handler NAD+ pathway precursor, published in Nature Medicine

Zinc + Magnesium + Vitamins 100% RDI Essential cofactors that make the other actives work

Every batch of CLADETM Longevity Complex is independently tested by a third-party laboratory for purity, potency, and heavy metals (lead, mercury, arsenic, cadmium). Certificates of analysis are available upon request. We test what we claim because transparency isn't optional.

Dosage: Take 3 capsules daily with a meal.

Why 3 capsules: Six active compounds at proper doses require adequate capsule volume. Three capsules deliver 984mg of active ingredients without compression or underdosing.

Tip: Take in the morning with breakfast for optimal NAD+ precursor absorption. Consistency matters more than timing.

Supply: Each bottle contains 90 capsules (30-day supply). 90 CAPSULES · 30 DAY SUPPLY.

Supplement Facts

Serving Size: 3 Capsules | Servings Per Container: 30

Resveratrol 95 300 mg

Vinomerix Optima® 210 mg

NMN (Nicotinamide Mononucleotide) 255 mg

Testosurge® (Apigenin-rich Fenugreek) 150 mg

Trigonelline 50% 60 mg

Zinc (as Zinc Bisglycinate) 11 mg (100% DV)

Magnesium (as Magnesium Glycinate) 420 mg (100% DV)

Wheat Germ Oil 9 mg

Methyl Folate 100% DV

Vitamin B12 100% DV

Other ingredients: plant-based capsule (hypromellose), rice flour. No artificial additives, fillers, gluten, dairy, soy, or GMOs.

Third-Party Tested

6 Actives

Published Research

90-Day Risk-Free

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Built for people who want longevity support without the stack chaos

The page should quickly tell a buyer whether they are here for simplification, better pathway coverage, or a more defensible longevity routine.

Stack fatigue

You are tired of managing five separate longevity products

Too many bottles, too many renewals, and too much mental overhead to stay consistent.

CLADE is positioned as a simpler daily protocol instead of another stack expansion.

Beyond NMN alone

You know one pathway is not enough

You have already learned that NAD+ talk alone does not equal full longevity coverage.

The page makes the five-pathway logic easier to believe and easier to buy.

Healthy-aging consistency

You want something you can realistically stay on

You care about long-term support but do not want a fragile routine held together by perfect discipline.

CLADE compresses the story into one clearer protocol with fewer ways to fall off.

Evidence-first

You want more than aspirational longevity branding

You read the science and want claims that feel more structured than category hype.

Transparent dosing and pathway framing give the page stronger credibility.

The NAD+ And Polyphenol Cellular Protocol

Most longevity supplements produce NAD+ and ignore the enzyme destroying it. CLADETM covers production, protection and the antioxidant side in a single daily dose.

Active 1

Polyphenol Defense

Resveratrol 95 · 300mg

One of the most studied polyphenols in longevity research. The bottle most people buy separately, dosed here on the label.

Active 2

OPC Reinforcement

Vinomerix Optima® · 210mg

Concentrated grape-derived OPCs. A different class of polyphenol that backs up the resveratrol instead of duplicating it.

Active 3

NAD+ Production

NMN 255mg + Trigonelline 60mg

Two distinct precursor routes boost cellular fuel. Trigonelline published in Nature Medicine.

Active 4

NAD+ Protection

Testosurge® · 150mg

Blocks CD38, the enzyme that destroys 90% of your NAD+ as you age. Producing NAD+ without protecting it is waste.

Active 5

Foundation

Wheat Germ Oil + Zn, Mg, Folate, B12

Essential cofactors at full daily values. These make everything else work. Not token amounts.

Standalone NMN $45 + resveratrol $30 + grape seed OPCs $15 + minerals $32 = about $122/mo at mid-market prices, CD38 still unprotected

CLADETM: $79/mo for all six actives

One protocol. Every dose printed. No CD38 gap.

What most people notice when they stay consistent

Longevity protocols work best when they are simple enough to stay on and broad enough to matter.

Week 1-2

Energy stabilizes, sleep deepens

NAD+ precursors begin restoring cellular fuel. Most users report steadier energy without the afternoon crash. Sleep quality improves as mitochondrial function begins to normalize.

Week 3-4

Mental clarity sharpens, recovery accelerates

Polyphenol antioxidant support settles in. Cognitive function feels noticeably sharper. Post-exercise recovery time decreases. Morning stiffness reduces.

Week 6-8

Compounding effects become measurable

Protected NAD+ has accumulated instead of leaking away. HRV improvements become trackable. Sustained all-day energy is the new baseline, not the exception.

Month 3+

Deep cellular renewal established

All six actives operating at full capacity. Consistent energy, cognitive clarity, and physical resilience. Biomarker improvements visible in bloodwork. This is what cellular maintenance feels like.

What Changes When Every Pathway Is Active

Before

Afternoon energy crashes by 2pm
Brain fog you blame on age
Waking up stiff with slow recovery
11 pills across 5 different bottles
$122+/mo and still no CD38 protection
"Aging is inevitable, right?"

➔

After

Sustained energy from morning to evening
Sharp, clear thinking all day
Faster recovery, better sleep quality
3 capsules. One protocol. Done.
$79/mo for the complete protocol
"Aging is modifiable."

Why Production Alone Fails

Producing NAD+ Is Half The Job. Keeping It Is The Other Half.

Standalone NMN targets production. A resveratrol bottle targets oxidative load. A mineral tub covers cofactors. Each addresses one piece, and none of them touch CD38, the enzyme destroying up to 90% of the NAD+ you just paid to produce. CLADETM is designed as a system: produce NAD+ through two routes, protect it from CD38, back it with two distinct polyphenols, and supply the cofactors that make it all work.

The CD38 Problem Nobody Talks About

Taking NMN Without CD38 Protection Is Like Filling a Leaking Bucket

CD38 is an enzyme that increases with age and inflammation. It consumes NAD+ directly, destroying up to 90% of your cellular fuel reserves. Most NMN supplements ignore this entirely. Testosurge (standardized apigenin-rich fenugreek) at 150mg blocks CD38 activity, meaning more of the NAD+ you produce through NMN and Trigonelline actually reaches your cells. With 255mg NMN plus CD38 protection, your net NAD+ accumulation can exceed what 500mg NMN achieves when CD38 goes unchecked.

Two Polyphenols, Not One

510mg Of Polyphenols Built In. Most NMN Stacks Skip Them Entirely.

Oxidative load climbs with age in exactly the tissues working hardest, and an NMN capsule does nothing about it. CLADETM carries Resveratrol 95 at 300mg alongside Vinomerix Optima® grape-derived OPCs at 210mg. Two distinct classes of polyphenol, 510mg combined, both printed on the label. The real value is that they sit in the same capsule as the NAD+ system rather than in two more bottles on your counter.

Why CLADE feels stronger than buying longevity ingredients one by one

Actives covered

Uncoordinated (no CD38, no cofactors)

Polyphenol dose

510 mg (Resveratrol + OPCs)

Separate bottles

CD38 protection (NAD+ shield)

✓ Testosurge 150mg

✗ Not included

NAD+ precursor routes

2 (NMN + Trigonelline)

1 (NMN only)

Essential cofactors (Zn, Mg, Folate, B12)

✓ Full RDI

✗ Buy separately

Daily capsules

8-11 across brands

Every dose on the label

✓

Varies by brand

Monthly cost

$79 (or $65 quarterly)

$122+ across four bottles

Third-party tested

✓

Varies

Different longevity goals. One simpler protocol.

★★★★★

"Consolidated from 5 supplements to 1"

I was the guy with the weekly pill organizer and a big monthly supplement budget. A standalone resveratrol, a grape seed extract, NMN, plus magnesium and zinc. When I calculated the overlap with CLADETM, it was a no-brainer. Two months in and my Oura ring data backs it up: HRV is up, resting heart rate is down.

★★★★★

"The formulation logic is sound"

Most longevity stacks are marketing-driven assemblages. CLADETM actually addresses the CD38 degradation problem that makes standalone NMN supplements wasteful. The inclusion of Trigonelline for the Preiss-Handler NAD+ pathway after the Nature publication shows someone is reading the literature, not just the competitor labels.

★★★★★

"Pill fatigue was killing my consistency"

I know the science. I've been following Attia and Huberman for years. But taking 11 capsules every morning across four bottles was unsustainable. I'd skip days, forget bottles when traveling. Three capsules a day, every day, no exceptions. Consistency is the actual longevity intervention here.

★★★★★

"My afternoon brain fog vanished"

At 58, I accepted that the 2pm mental fade was just part of aging. Four weeks into CLADETM, I realized I'd been working straight through to 5pm without noticing. My husband started taking it after seeing the change in me. Neither of us are willing to stop now.

★★★★☆

"The CD38 blocking is the real story"

Everyone talks about NMN dosing, but the Testosurge CD38 blocker is the underrated piece here. I was taking 500mg NMN alone and not seeing the results I expected. CLADETM gives you 100mg NMN with CD38 protection, plus four other pathways. I'm a biohacker who tracks everything, and my recovery metrics improved more in three weeks than months of standalone NMN.

★★★★★

"I was paying more for less and still missing CD38"

I did the math on my old stack: NMN at $45 and the minerals at $32 came to $77 before I even counted the resveratrol and the grape seed extract, and I was still missing CD38 protection entirely. CLADETM covers everything for $79 on the monthly plan. The synergy design justified the switch, but the results confirmed it.

Dosed in the Optimal Zone

After studying hundreds of clinical research reports, we dosed every ingredient at the exact level where published data showed peak efficacy. Not underdosed to cut costs. Not overdosed to impress on a label. The precise dose where biology responds best. You can finally stop second-guessing.

Resveratrol 95 (Polyphenol Defense) 300 mg